Xiling Shen Publications
The Cancer Microbiome Atlas: A Pan-Cancer Comparative Analysis to Distinguish Tissue-Resident Microbiota from Equiprevalent Contaminants." Cell Host & Microbe (In Press).
"Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity." Nature Communications 12, no. 1 (2021).
"The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress." Nature Communications 11, no. 1 (2020).
"The cancer microbiome atlas: a pan-cancer comparative analysis to distinguish tissue-resident microbiota from contaminants." Cell Host & Microbe (2020).
" "A Deep Learning Approach to Analysis of Kidney Transplant Frozen Sections." In Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 1573. Vol. 33., 2020.
"Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer." Bmc Cancer 20, no. 1 (2020).
"Electrical stimulation can delay fluid propulsion during motor complexes in mouse colon." In Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. Vol. 32., 2020.
"An imprecise path to precision medicine." Nature Medicine 26, no. 1 (2020).
"Intravital imaging of mouse embryos." Science 368, no. 6487 (2020): 181-186.
"A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer." Mol Cancer Ther 19, no. 12 (2020): 2516-2527.
"Single cell transcriptomics of mouse kidney transplants reveals a myeloid cell pathway for transplant rejection." Jci Insight 5, no. 20 (2020).
"Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration." Jci Insight 5, no. 22 (2020).
"A Tissue Engineering Approach to Metastatic Colon Cancer." Iscience 23, no. 11 (2020).
"Agent-Based Modelling to Delineate Spatiotemporal Control Mechanisms of the Stem Cell Niche." Methods in Molecular Biology (Clifton, N.J.) 1975 (2019): 3-35.
"Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo." The Journal of Immunology 202, no. 2 (2019): 608-617.
"Integrated chromatin and transcriptomic profiling of patient-derived colon cancer organoids identifies personalized drug targets to overcome oxaliplatin resistance." Genes and Diseases (2019).
"An intravital window to image the colon in real time." Nature Communications 10, no. 1 (2019).
"Mapping the microbial interactome: Statistical and experimental approaches for microbiome network inference." Experimental Biology and Medicine 244, no. 6 (2019): 445-458.
"Novel Three-Dimensional Cultures of Patient-Derived Cancer and Tumor Immune Cells." Gastroenterology 157, no. 1 (2019): 260-261.
"Physiological responses to sacral nerve stimulation in rodent colon." In Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. Vol. 31., 2019.
"SENP3-mediated host defense response contains HBV replication and restores protein synthesis." Plos One 14, no. 1 (2019).
"Abstract 5479: Targeting fructose-induced metabolic reprogramming in liver metastasis." In Molecular and Cellular Biology / Genetics., 2018.
"Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis." Cell Metab 27, no. 6 (2018): 1249-1262.e4.
"Computational motility models of neurogastroenterology and neuromodulation." Brain Research 1693, no. Pt B (2018): 174-179.
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